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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4fb48387c8eeed279b3631223391f736ed7dfe598305fd003fc1a25825b6c28' 
  AND token = 'Ldeiti0/EJYVIhjDWj3opK4IWcHsGSgc5KJr/HKFVcg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}