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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c81b9b4b710f39e47eb2de5e62b5c3a1fe990357b02e1fc3a05b4eede87db66c' 
  AND token = 'oCgezorwjWZ6LKXCoMpoAmFhdLWtQ/3SAs5T0YoL5p8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}