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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b6a8d8614781c9dc12ee4c4809ddbcdbee37ec6cae847d4c297469a23d724417' 
  AND token = 'fgDx43eKIQ4cEECJHbS4ocgVL8IpktKBVIFLrqri+Ls=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}