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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2356af8ea735581047ca801271bdd58e5e8f8e3c059ab39ee8193a0332b17566' 
  AND token = 'ezDxzbwqxCWOqhF3dvPhTw09CpK1iEvKihsT0GIhF4E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}