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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a3855f9667faa3cf9b5322c9422a98b388839dde4b880b805f51a6622e098e4' 
  AND token = 'LN+jASiamAtzTZQQRPks3PYCCAVoTenRdlpFDFUlvv8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}