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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0180319ecfda2c84a4cdd455fe283bde4fd71302c4a150758cf3d962f299d528' 
  AND token = 'oizA5wc+Qc5SU3tX3FRrJ6u1thFYbT9oImYQOD24AIM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}