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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e29710aa54bd5444724768e40c6ce24c9360482416e5dd83258bd7a0bd2175b' 
  AND token = 'UPtUS/n4ujpCsadSX/6ny3p+xr1WSd8IhhTH2UjjRB0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}