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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0308c5c571a7503894399389667c5eb9c9c22826ac1239f60e395475f2dfe374' 
  AND token = 'd9c6YkO399KUAJfxSMKH/OaPwWMPx5R1bDjgBemtN0U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}