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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ccf49177a2fcb8a2d09fec454df2742ae95eeb1606d67f2a43a072065cd1c93a' 
  AND token = 'Gf0Ll/w0dxgMWahuJ04nAJWW4CVhloU6bU2mW3ojKdg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}