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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7022ab2f4a5a524cceee379e9caddd9f9aa7eceac7677f49adef930f05f852df' 
  AND token = 'cNBjc3330PK4Ogi7kSJrD2tT9kaN3XAVj/Ic20EC/7A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}