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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e6cdd800dd3b0d919da27e0b80c52855e0d2d96137e623cfb5b1be8df2888d4' 
  AND token = 'Fzz2egDRj+0Rc6SyyhiZpfhPGe2j9hnGHRjYlnEmJ10=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00061

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}