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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e874328104e9e79308318faad7a79874e87c95fadb6c10609d21fc8b0d3d609' 
  AND token = 'DU5E0ay3CJSPzmbb2blGYCBWAiaD3GRM89svs97vlTo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}