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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e709703b7b1092e4c06d59511720fa699da511a41ea66be9135aa8e969b5d48f' 
  AND token = 'xAaxQODsn3fr31VtSYh4l9I+otRYQzhs75VDoeyIUMM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}