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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f5049c50b7c526e9689a41cc50a9707b442d6dfdeea50686bb337ce0a02f2c73' 
  AND token = 'dmQVggrm2Gn9LtQ104MukUs9RjOdiR38cxwvqE0c+ho=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}