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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3ea45fac4073e0b707065a376421db5d5ce290182c6c65e7f88a1ca672c865e8' 
  AND token = 'tqzD4+B52zoqhTnIGQ4+86P4PWtQ+kMv38xDAFNIZrw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}