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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd68bf160038b3a2c3b8424aad77e76dceb95ab19281f684da2688e289a11d3aa' 
  AND token = 'lL9JC9u3U7DCDR6H5WfqyW+OItOm6znrJroAjvqy624=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}