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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '602ef9a1272203087aa3d233f79e35a5dc075b1d856004118c52997c13d90a42' 
  AND token = 'gDzG1A/iIG/JSBTwO4a0ZZV3/MG6fi88wTa2qw6g3ck=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}