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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f0afd7404ced5899b7656094d4dfa8234c7662bd7232a7e398de6cea63f6e59' 
  AND token = '5D/FX7+vur0JoHNkhrhKH7jUEd8v/Dhib664YXPKCCU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}