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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '14fac37840cd84336f2901a1a20841c25a4e498cc7ccb47812febb1c3925ed42' 
  AND token = '7Qn5AtX+ni/ROJKMs7NYYYSmuZ2R5x5QkhKO7LX+wZw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}