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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c4461d4e129d9c6983b4c81290ecae8f2b4ee9ecc5ddd865426395e2ad45554d' 
  AND token = 'AyNGuMf9XIRcv6fEbAKue1bONiwYA0hoE4tBKPUQ6Vs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}