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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '308e7e6da86e777066a4cbd7cba761436502e395377af1fd9d1753c52d681bf1' 
  AND token = '4MFi0voE/NADC3x/4lnUbSf37N/QoOwMJi2rfuexkuA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}