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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2c70f6d2eb4cd5fb64872f8e4fbd94ad4c342ae6acb7e1e4347395f934443af' 
  AND token = 'QPGP+8j3OJrMPoqLej67uZxxLGxQHA1fYP+N1I4i/J4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}