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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80fe687b6e65ca9bc7d8057c4ff9076bd9e26d306a471f512ecfe2ce7ce23d07' 
  AND token = 'jO29xfzY8QXYQTUNYYjRi/8j9GOBnrsrjp14ynzKpD0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00050

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}