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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7bb6eeb9b701e9f85c833c17d5a280ea767111f6978e1f4e9459154169a021a3' 
  AND token = '0ISZ9mRglnY3y/Yx8ODvsU+XAlyxv7fjOrFRJAI9lxM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}