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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b1bd5def0caab306b8213f02a820a4efb0d917d56867a61eb6a95d4d0e2ec01' 
  AND token = 'N/2Oesebpc4mTGNUQskfqzMJWUrbdUuCmcCuX9925uk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}