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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d3edc225e1cdf101e0d52a4adf6e3d125a3daf5e471ac254f465ecb5150a989' 
  AND token = 'W4sp7juiL/Hk4VkVX4Fdl0GEtJLE2xkDw7Vjkoa1vAU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}