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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12cff6432adf796cf9df2eb27a36d5899cd0a695d494a8bcecbce4e7a11a73a3' 
  AND token = 'dJ3r3co8enZTA5ecwfvEVKpKUh+FOpsZ1asU7BOS4Ig=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00061

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}