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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '454cdfbdf8c20721a7e3c3e8ee86b4852caee14c5296aeb15443ed3ae2031b43' 
  AND token = 'FUJfiwYd25G+5jzsTln9IuWGMaATIlrXfoiJ8RxwFcA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}