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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d6d95a4283c9d0f422af3dea6a4fd42d5b399f6f425b007dbafbc7e054a3f42' 
  AND token = 'faYISEVU7ZXDjizOC9v0HWNKC0sl17b2UfTuCddLGY4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}