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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e18d20800b4e787f20705bda42726ee6add7f6e685bdcfcfb8340705d9f99ec1' 
  AND token = '+uHb+w1/Aqq2EjVG8DzwaMPmn9/E0cFhjqd5APM4CAA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}