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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '324e61c270b577251230193255451fc58c5650318f4d57afbfa7e8a058bba60d' 
  AND token = 'j0aQpX7LBIbtYQ4Zv4L/R9WMENiVpVsRp8GG7tYP25w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}