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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c3b73d4d681fc6b7c9e91e9a394272a1f8c2c60188ae58e5f4e2a436b2fa836' 
  AND token = '5kkfQB1BrNm/7YAvfQfEwt0lp3Tixw1jmtuENG0IjDs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}