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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5aa4091734ada4f6c9cf9e1fc50fbd7a9ea926e94d7160077fdb30940a3ff8b5' 
  AND token = '0xxqBZ+GqVd7x4iTMdajYVqFYmtfrt+pVwna3oW6KpU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}