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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80186d5b6563184e9f0e44d001bf470cdb00e786ddaf2879dc8bccc1b76e6df8' 
  AND token = 'r7qugDNdVxCf8/MKP0VXML4I8/dnNHEnkL1Pe2/Pymw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}