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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9ce412c2422b0c010dc1b640ef879999952a1802769221e6c70f959ccbf4618b' 
  AND token = 'OSUFMwkzHUUhzcZELN9qd1g+oxKRUzxN0R52lZycU7o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}