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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f642c0eb68b925caad3981c03ed4dc9e8743fd688374714288202082ac06b40' 
  AND token = '23L6Vz9uHYVgp3tgkAK+4w4wr90IYNefFBrT5/Z6uP8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}