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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e1fa3e01185b7186b79dd8fc968265126f1df890aee7a3a6d030d8d7feca213' 
  AND token = '0wm+kkhAPrP5DMlIaYqpRZZhK42yf3D6R2iLZIPz4Ec=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}