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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8572b199431495334907019897bd51bb8d367e11bde60a8712608d04806d2adb' 
  AND token = '+RQr5doyJzUVhbmATV6UBjvSunaeUNa5Zl/vhV4GoTc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}