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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df7750ea069b6a4ed1b01d7101545120e1c47eae8d2a80c728d1b296cba4554b' 
  AND token = '5xBQuRnYElKU67O7eojjvi4r2WgXnd3wwSXyCt9U9xQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}