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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '387b523ec9970a6a7b6bdec1e2794bf643a5c553ddcafcde8cea975bd543a3b5' 
  AND token = 'IgZDSbE5gB5C+DSn5m54tKw3vVEiCv/YRfrlg8Gpxgk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}