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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '082375f8543cf2648cd40e6d81c3be009b3c24b05c6ad6f1549c12146ee728c7' 
  AND token = 'deTWSG6r1Js4dqpCjeDZD353pdlV7i06ABm29lE2bOM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}