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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de19dd310c871653f78c5a4c5e4d6b96d530464b5b3563d7c3cd74520ecc00b4' 
  AND token = 'n7jxdQaUTweP6MuhuALEzGUjhMz3TsmeYsqKpiSygOs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}