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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '77173aa644e5584d14b44f476e15d56990b7b45504843ca5be58ced475225029' 
  AND token = 'JQtOI3IHSRJXsTPo6IOjm6YtTZ/lCV9/H71LFjWFMD8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}