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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a704d688250f79fb471f792c3f678d04469b76b12e20be11aaa2205080e90b4' 
  AND token = 'JmRmgYBfkQU0WOGZNfE2Pk3t/JW81/66/c0/7XNpp5k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}