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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1bb927c1ebf00faf549c3b6d037cb4cc6e96bd5da42d97c36fee513d154bc27d' 
  AND token = 'Py+qLbizKrg3YQfsz0Je1qUupc678ESHvIb7SOPVBhQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}