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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7d14ab42b4cb82cdcad2df14db2c50c9fdf6083a575e2d6a2dbe21966357aeea' 
  AND token = 'vZdUUdIM5qpaD40X5yVwrrpPdgSiyvaFuKv7yrOq/Pg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}