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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5defc9e43b995ce08cd2e9983d8f416cb111ff234afb31a714a6ce4fe14e7c85' 
  AND token = '++sz8/+nDM4iCEDtozKCihtxJhrdN5xG+hGuCn5wSsM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00073

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}