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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '24da0c7eea91226b23459dc4d4f458cecabdbef1b469fba8571cf13d83e72f76' 
  AND token = 'io/5etbcJl+QOlkTUEHPwTpzSacbKWoYt8i/mbnV1r8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}