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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b6122a30996be75b46606665d674106033a3c6d6c4cbdcb1f9dc53a0254c7620' 
  AND token = 'w8gddrBmNO2amc1nsOSmy5qjX8S0UQcyX8aOmH/X6Nw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}