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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f74fad5e64727c01e5bb4c10fdb52c84653ea8c1d2612aac60e44224863cec8' 
  AND token = 'RAHoIlbDJCzDKAiZLN9fmbx2E1IbqzFHIjN1NfJNZuU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}